ANTIBIOTICS SUSCEPTIBILITY PATTERN OF SOME SELECTED BACTERIA (BATONELLA, BACILLUS, SALMONELLA) ASSOCIATED WITH URINARY TRACT INFECTION AMONG PATIENT'S ATTENDING GENERAL HOSPITAL MINNA NIGER STATE

ABSTRACT

Urinary tract infections (UTIs) represent a significant public health issue, often complicated by the rising prevalence of antibiotic-resistant bacterial strains. This study investigates the prevalence and antibiotic susceptibility patterns of Bartonella, Bacillus, and Salmonella isolated from UTI cases among patients attending General Hospital Minna, Niger State. A cross-sectional design was employed, with bacterial isolates obtained from urine samples subjected to culture, biochemical tests, and antibiotic susceptibility testing using the disk diffusion method. Statistical analysis, including chi-square and ANOVA, revealed that Bartonella was the most prevalent isolate, demonstrating high resistance to commonly prescribed antibiotics such as amoxicillin-clavulanate and trimethoprim-sulfamethoxazole. Salmonella exhibited relatively low resistance, maintaining susceptibility to first-line antibiotics, while Bacillus showed moderate resistance but remained susceptible to gentamicin and nitrofurantoin. The study underscores the need for localized antibiotic guidelines and the importance of routine culture-based diagnostics in optimizing UTI treatment. This research highlights the critical role of antibiotic stewardship in mitigating the spread of resistance, advocating for region-specific treatment protocols and responsible antibiotic use. Limitations include the study's single-site focus, which may restrict generalizability. Future research should explore broader geographical areas and employ molecular techniques to understand the genetic mechanisms of resistance. These findings provide a foundation for informed clinical decisions, public health policy adjustments, and ultimately, better management of UTI-related antibiotic resistance in the study region.